AKI Trial Matcher — Prototype (v0.1)

Nephrology → Acute Kidney Injury · published/completed landmark RCTs only · no ongoing/recruiting trials

Prototype — verify before clinical use. Trial eligibility criteria below were pulled directly from the ClinicalTrials.gov registry record for each NCT number on 2026-08-05, but the structured field mapping was done by Claude and has not been independently checked against the published manuscripts. Cross-check against the original papers before relying on this for a real patient decision. This tool never guesses on a value it wasn't given — any missing input is shown as "cannot determine," never folded silently into a yes/no verdict.

Demographics & setting

Age (years)

Sex

In ICU?

Mechanical ventilation?

Vasopressors / catecholamines?

Weight (kg)

Renal function & labs

Current serum creatinine (µmol/L)

mg/dL × 88.4 = µmol/L

Known baseline/pre-morbid creatinine (µmol/L)

Creatinine clearance / eGFR (mL/min)

Serum urea (mmol/L)

BUN mg/dL × 0.357 = urea mmol/L

Serum potassium (mmol/L)

K+ 5.5–6 persisting despite treatment?

Serum bicarbonate (mmol/L)

Arterial pH

Urine output & AKI timing

Urine output, mL/kg/h over preceding 12h

Oliguria duration (hours, <0.3 mL/kg/h or <500 mL/day)

Anuria duration (hours)

Hours since severe-AKI criteria first met

Cause of AKI

Clinically significant pulmonary oedema w/ severe hypoxemia (in setting of AKI)?

One non-renal organ failure or sepsis?

RRT / dialysis history

RRT already started this admission for current AKI?

Hours since RRT started (if applicable)

# HD sessions this admission (if applicable)

Any RRT within previous 2 months?

On chronic maintenance dialysis before admission?

Prior kidney transplant?

Days since transplant (if applicable)

Other exclusion-relevant factors

Pregnant / breastfeeding? (if female)

Child-Pugh class C cirrhosis?

Ingestion of a dialyzable toxin/drug requiring RRT?

Cardiac arrest without awakening?

Treatment limitation / comfort-measures-only / moribund?

Not expected to survive 28 days (terminal condition)?

Incarcerated / under legal protective measure?

Clinician judgment / RRT decision-making (optional)

Clinician believes immediate RRT is mandated?

Clinician believes deferral of RRT is mandated?

CRRT considered/planned by treating team?

Anticipated to need CRRT ≥72h?

Oliguria unresponsive to fluid resuscitation?

Leave any field blank if unknown — it will show as "cannot determine," not guessed.